Clustal W and Clustal X version 2.0

نویسندگان

  • Mark A. Larkin
  • Gordon Blackshields
  • N. P. Brown
  • R. Chenna
  • Paul A. McGettigan
  • Hamish McWilliam
  • Franck Valentin
  • Iain M. Wallace
  • Andreas Wilm
  • Rodrigo Lopez
  • Julie Dawn Thompson
  • Toby J. Gibson
  • Desmond G. Higgins
چکیده

SUMMARY The Clustal W and Clustal X multiple sequence alignment programs have been completely rewritten in C++. This will facilitate the further development of the alignment algorithms in the future and has allowed proper porting of the programs to the latest versions of Linux, Macintosh and Windows operating systems. AVAILABILITY The programs can be run on-line from the EBI web server: http://www.ebi.ac.uk/tools/clustalw2. The source code and executables for Windows, Linux and Macintosh computers are available from the EBI ftp site ftp://ftp.ebi.ac.uk/pub/software/clustalw2/

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Performance Optimization of Clustal W: Parallel Clustal W, HT Clustal, and MULTICLUSTAL

Multiple sequence alignments represent a class of powerful bioinformatics tools with many uses in computational biology. Knowledge of multiple alignments (MA) helps to predict secondary and tertiary structures and to detect homologies between newly sequenced genes and existing gene (protein) families. With the adoption of high-throughput (HT) automation, offering scientists significantly more d...

متن کامل

Parallel CLUSTAL W for PC Clusters

This paper presents a parallel version of CLUSTAL W, called pCLUSTAL. In contrast to the commercial SGI parallel Clustal, which requires an expensive shared memory SGI multiprocessor, pCLUSTAL can be run on a range of distributed and shared memory parallel machines, from high-end parallel multiprocessors (e.g. Sunfire 6800, IBM SP2, etc.) to PC clusters, to simple networks of workstations. We h...

متن کامل

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools.

CLUSTAL X is a new windows interface for the widely-used progressive multiple sequence alignment program CLUSTAL W. The new system is easy to use, providing an integrated system for performing multiple sequence and profile alignments and analysing the results. CLUSTAL X displays the sequence alignment in a window on the screen. A versatile sequence colouring scheme allows the user to highlight ...

متن کامل

PyMod 2.0: improvements in protein sequence-structure analysis and homology modeling within PyMOL

MOTIVATION The recently released PyMod GUI integrates many of the individual steps required for protein sequence-structure analysis and homology modeling within the interactive visualization capabilities of PyMOL. Here we describe the improvements introduced into the version 2.0 of PyMod. RESULTS The original code of PyMod has been completely rewritten and improved in version 2.0 to extend Py...

متن کامل

A Clustal Alignment Improver using Evolutionary Algorithms

Multiple sequence alignment (MSA) is a crucial task in bioinformatics. In this study we extended previous work with evolutionary algorithms (EA) by using MSA solutions obtained from the wellknown Clustal V algorithm as a candidate solution seed of the initial EA population. Our results clearly show that EAs can improve the results of Clustal V significantly with marginal computational effort.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Bioinformatics

دوره 23 21  شماره 

صفحات  -

تاریخ انتشار 2007